The use of a P. falciparum specific coiled-coil domain to construct a self-assembling protein nanoparticle vaccine to prevent malaria
Abstract Background The parasitic disease malaria remains a major global public health concern and no truly effective vaccine exists.One approach to the development of a malaria vaccine is to target the asexual blood stage that results in clinical symptoms.Most attempts have failed.New antigens such as P27A and P27 have emerged as potential new vac